Nā huahana
ʻO Doxifluridine
Hui Pū ʻIa
Kikino
ʻAno: keʻokeʻo Paʻa
Māmā:1.3751 (manaʻo)
Lae hehee:188-192 °c(L.)
Ka Po'i Pono: d25 +18.4° (c = 0.419 I loko o ka wai)
Hoʻohālua: 20 °(c=1, H2o)
Ke kūlana mālama: inert Atmosphere, lumi wela
ʻO ka Acidity Factor(pka): 7.4(ma 25 ℃)
ʻIkepili Palekana
Māhele pōʻino: ʻAʻole nā mea pōʻino
No ka lawe ʻana i nā waiwai pōʻino:
Māhele Packaging:
Palapala noi
1. E like me ka prodrug o 5-Flurouridine.ʻO kahi nucleoside pyrimidine fluorinated me ka hana cytostatic.Hoʻohana maʻi no ka maʻi maʻi ʻōpū, ka maʻi maʻi colorectal, ka maʻi maʻi umauma, hiki i ke kala kala ke piʻi ma mua o 30%
2. Ma keʻano he kikowaena no nā lāʻau antitumor Fluorouracil
Hoʻolauna i nā hoʻohana
1. ʻO nā lāʻau antitumour e pili ana i ka Fluorouracil he mau mua ia no ka fluorouracil.ʻO ka enzyme thymidine phosphorylase, aia i loko o ka ʻiʻo tumo, hana ia e hoʻololi iā ia i fluorouracil i loko o ka puʻupuʻu, no laila e hana ana i kahi hopena anti-tumor.Loaʻa iā ia kahi kikoʻī anti-tumour ikaika a haʻahaʻa haʻahaʻa.Hoʻohana ʻia ia i ka maʻi maʻi ʻōpū, ka maʻi maʻi colorectal a me ka maʻi maʻi umauma, me ka helu kala ʻana a hiki i 30% a ʻoi aku paha.
2. Lapaʻau waena.
3. He lāʻau antitumour ia, he lāʻau lapaʻau mua o ka fluorouracil (5-FU), i hoʻololi ʻia i fluorouracil manuahi e ka hana o ka pyrimidine nucleoside phosphorylase i loko o nā ʻiʻo tumora, pēlā e kāohi ai i ka biosynthesis o DNA a me RNA i loko o nā pūnaewele tumora a hōʻike i kāna. hopena antitumor.No ka mea, ʻoi aku ka kiʻekiʻe o ka hana o kēia enzyme i loko o nā ʻiʻo tumo ma mua o nā ʻiʻo maʻamau, ʻo ka hoʻololi ʻana o 5-FU i 5-FU i loko o nā ʻiʻo tumo he wikiwiki a koho no nā ʻōpū.Hoʻohana ʻia ia i ka mālama ʻana i nā maʻi kanesa o ka umauma, ka ʻōpū a me ka rectal a he haʻahaʻa haʻahaʻa.
