Nā huahana
Adenosine
Hui Pū ʻIa
Ke ʻano: keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline keʻokeʻo keʻokeʻo
Māmā: 2.08 g/cm³
Ka helu hehee: 234 a 236 ℃
Puni paila: 676.3 ℃
hoʻohalahala: 1.907
Kaila uila: 362.8 ℃
ʻIkepili Palekana
Māhele pōʻino.
Helu lawe waiwai weliweli.
Māhele ʻeke.
Palapala noi
Hoʻohana ʻia ka Adenosine e kōkua i ka hoʻihoʻi ʻana i ka puʻuwai maʻamau i nā poʻe me kekahi mau maʻi puʻuwai puʻuwai.
Hoʻohana pū ʻia ʻo Adenosine i ka wā o ka hoʻāʻo koʻikoʻi o ka puʻuwai.
Hiki ke hoʻohana ʻia ka Adenosine no nā kumu ʻaʻole i helu ʻia ma kēia alakaʻi lāʻau lapaʻau.
ʻO Adenosine, he pūhui N-9 o ka adenine i hoʻopili ʻia me C-1 o D-ribose e kahi paʻa β-glycosidic, loaʻa ke ʻano kemika C10H13N5O4 a ʻo kāna ester phosphate he adenosine acid.ʻO Adenosine kahi nucleoside endogenous e laha ana i loko o nā pūnaewele kanaka a hiki ke komo pololei i ka myocardium e hoʻohua i ka adenosine acid e ka phosphorylation, ka mea e pili ana i ka myocardial energy metabolism, a me ka hoʻonui ʻana i nā moku coronary a me ka hoʻonui ʻana i ke kahe koko.Hoʻohana ʻia ia i ka mālama ʻana i ka tachycardia supraventricular.Loaʻa i ka Adenosine nā hopena physiological i ka ʻōnaehana cardiovascular a me nā ʻōnaehana ʻē aʻe a me nā ʻiʻo o ka ʻiʻo.ʻO Adenosine kahi mea koʻikoʻi waena i hoʻohana ʻia i ka synthesis o adenosine triphosphate (ATP), adenine, adenosine acid, a me adenosine asiaticum.
He mea antiarrhythmic hoʻi ia e hoʻohuli i ka paroxysmal supraventricular tachycardia i ka sinus rhythm.Hoʻohana ʻia ia no nā arrhythmias supraventricular e pili ana i ka atrioventricular.Hoʻomaʻamaʻa i ka angina pectoris, myocardial infarction, coronary insufficiency, atherosclerosis, hypertension pono, cerebrovascular disorders, post-stroke sequelae, progressive muscle atrophy, etc. Hoʻohana pū ʻia i nā haʻawina biochemical.
ʻO Adenosine he purine nucleoside endogenous e hoʻolohi i ka hoʻokele ʻana o ka node AV, poloka i ke ala o ka nodal fold AV, a hoʻihoʻi i ke kani sinus maʻamau i nā poʻe maʻi me ka paroxysmal supraventricular tachycardia (PSVT) (me ka preexcitation syndrome a i ʻole.Lawe koke ʻia ʻo Adenosine e nā ʻulaʻula ʻulaʻula a no laila he pōkole ka lōʻihi o ka hana, me ka hapalua ola o ka plasma ma lalo o 10 s.ʻO ke ʻano maʻamau o ka PSVT ma o ke ala retrograde, no laila ʻoi aku ka maikaʻi o ka adenosine i ka hoʻopau ʻana i kēia ʻano arrhythmia.I nā arrhythmias non-atrial a i ʻole sinus node regressive (e laʻa, atrial flutter, atrial fibrillation, atrial tachycardia, ventricular tachycardia), ʻaʻole hiki i ka adenosine ke hoʻopau iā lākou, akā hiki ke hana i ka atrioventricular a i ʻole ventricular block, hiki ke kōkua i ka hana ʻana i kahi hōʻailona ʻokoʻa.
